The need for mechanical ventilation is very climate and operation dependent.

Relative humidity is so low in Colorado that moisture build-up inside houses is very rarely a problem, not so in the Northeast and Northwest.

The first step for indoor air quality is to avoid introducing contaminants (unvented gas stoves are terrible). Not installing new indoor petrochemical products (carpet, upholstery, cabinet finishes,etc.) does a lot for IAQ too. If the solar gain area is slightly oversized, rather than mechanical venting, simple convection venting by opening a high window on sunny days is quite practical.

I've also been in old houses in Baltimore that simply have a fan in the attic, and no air conditioning. They had high ceilings in each room. They were quite cool, and in a Baltimore July that is saying something!

I'm thinking a lot of these older strategies will be rediscovered.